Home/ Products/ Indications
Indications & Clinical Use

Where patient-matched reconstruction makes the difference.

From severe traumatic brain injury decompressive craniectomy to aesthetic craniomaxillofacial (CMF) reconstruction, our implants are designed to address the indications where standard solutions have failed patients the most.

Skull Reconstruction — Indications

Cranial defect repair & reconstruction.

Class III indication for the Patient-Matched Skull Reconstruction System (Models DLZ04, DLZ05).

Adult

Severe TBI + decompressive craniectomy

Young 20–50 yr, 70% male. Large, irregular defects — often bifrontal. High infection risk with conventional mesh.

Adult

Ischaemic stroke + DC

Mid 50–70 yr. Hemispheric, large-area defects. The patient-matched geometry reduces operative time.

Adult

Aneurysm rupture

40–70 yr. Large, irregular defects. Multi-disciplinary team approach.

Adult

Brain tumour resection

40–70 yr. Often orbito-frontal or temporal defects. Aesthetic outcome matters.

Paediatric

Congenital deformity

0–10 yr. Dedicated paediatric sizes. Growing-skeleton considerations.

Paediatric

Paediatric trauma

5–18 yr. Paediatric size range. Long-term biocompatibility matters more.

Cosmetic

Aesthetic CMF

30–60 yr. Forehead and temporal contour restoration. Highest aesthetic expectations.

Re-do

Reconstruction after prior cranioplasty failure

Re-operation cases with poor soft-tissue envelope or contaminated field. Patient-matched geometry simplifies the case.

Oncology

Post-resection reconstruction

Oncological resection defects. Customised to match the resected volume.

CMF & Maxillofacial — Pipeline

Beyond the cranium. The same platform, broader reach.

The ME-Fab® platform is indication-agnostic. We are extending the same patient-matched architecture into the broader craniomaxillofacial space.

Orbital floor

Patient-matched reconstruction of orbital floor and rim defects from trauma or tumour resection.

Pipeline

Zygoma & malar

Custom zygomatic reconstruction with biomimetic micro-architecture for soft-tissue support.

Pipeline

Mandible

Patient-matched mandibular plates and segmental reconstruction. Coordinated with vascularised fibula flap when needed.

Pipeline
Spine — Pipeline

Interbody fusion. Engineered for bone ingrowth.

The same gradient porous micro-architecture, applied to cervical and thoracic interbody fusion.

Cervical interbody

Patient-matched cervical interbody cages with porous endplates for endplate-matched fusion.

Pipeline

Thoracic interbody

Patient-matched thoracic cages with gradient porous structure for load-bearing fusion.

Pipeline

Custom complex

Patient-specific complex spinal reconstruction for severe deformity or tumour cases.

Pipeline
Orthopaedic Trauma — Pipeline

Pelvis. Acetabulum. Long bone.

High-complexity, low-volume trauma reconstruction where patient-matched geometry solves the case.

Pelvic & acetabular

Patient-matched reconstruction for complex acetabular fractures and pelvic discontinuity.

Pipeline

Long bone non-union

Custom plates and scaffolds for revision surgery of long-bone non-union.

Pipeline

Oncological resection

Patient-matched endoprostheses for limb-salvage surgery after tumour resection.

Pipeline
Custom Solutions

One-off. One-of-a-kind. Made to order.

For cases that don't fit any product family, our team works directly with the surgeon on a custom-made device pathway.

Custom-made devices

Under MDR Article 52(4) and the equivalent regulations in other jurisdictions, we can deliver patient-specific implants for unique clinical situations. The custom-made device pathway is the most flexible regulatory route for one-off complex reconstructions.

  • Patient-specific complex reconstruction (e.g., post-trauma, post-oncology, congenital)
  • Imaging-based design, surgeon-engineer sign-off, full quality release testing
  • Regulatory pathway: custom-made device (EU MDR Art. 52(4)) or equivalent
  • Lead time: project-dependent, typically 4–8 weeks

Have a complex case?

Our clinical engineering team works directly with surgeons on complex and custom reconstructions. Tell us about your case.

Discuss your case Clinical decision tree