The strongest clinical evidence base in patient-matched CMF implants.
Complication rate comparison vs. literature controls.
Total complication rate
Infection rate
Large-cohort prospective. The evidence that procurement and HTA bodies look for.
Large-cohort prospective
Multi-centre, prospective, with active follow-up. Not retrospective. Not single-centre.
Peri-operative + mid-to-long-term follow-up
Safety and effectiveness endpoints tracked from index procedure through medium-term follow-up.
50+ clinical partner sites
Including FMMU, Southern Medical University, Shenzhen Second People's Hospital, Beijing Tiantan, Huashan, Xuanwu.
Standardised safety & effectiveness
Infection, re-operation, implant exposure, headache, loosening, subcutaneous effusion, total complications.
Peer-reviewed literature
Compared against published complication rates for titanium mesh and PEEK plates.
5,000+ cases and growing
Continuously updated post-market database. Real-world evidence continuously feeding design and process improvements.
Three clinical scenarios where the difference shows.
Severe TBI + decompressive craniectomy
Young 20–50 yr, 70% male. Large, irregular, often bifrontal defects. Infection risk is the dominant complication with conventional mesh — our < 1.7% infection rate vs. 6–8% with mesh translates to fewer re-operations and shorter inpatient stays.
Aneurysm rupture reconstruction
40–70 yr. Large, irregular defects. The MEI workflow collapses the traditional "try-fit, re-trim" loop into a single placement — saving 60–90 minutes of OR time per case.
Aesthetic CMF
30–60 yr. Forehead and temporal contour. The biomimetic dual-surface design and 1:1 curvature restoration deliver the natural aesthetic outcome that drives patient satisfaction.
Reviewed by the institutions that set the standard.
Guangdong Science & Technology Invention Award
Second Prize (2020) for core technical innovation in patient-matched AM.
10 national guidelines
Co-author of 10 national-level guidelines shaping 3D-printed medical device practice.
100+ publications
100+ peer-reviewed publications in materials science, biomechanics, and clinical outcomes.
Want the full clinical dossier?
We provide a Clinical Evidence Summary, full complication comparison, and references to procurement, HTA, and ethics committees under NDA.